
The Tahamies shared language and culture with the neighboring Nutabe, although they were clearly independent and autonomous from each other. This culture was expressed, economically, by their condition of very prominent farmers, although of rudimentary technology, owners of immense fields of corn, cotton, various fruit trees and beans. They also exploited fishing intensively in our abundant and rich tributaries.
Around 1530, Captain Francisco Núñez Pedroso began the Spanish colonization, suffering great hardships due to the difficult terrain. When he saw how difficult it was to access the mountains of Antioquia, he entrusted Juan Carreño to continue with his expedition, who invaded the lands of the Punchina and Nutabe cacique, reaching the banks of the Nare River.
The territory of San Carlos belonged to the domain of Cacique Punchina, the Spaniards named it the Valle del Corpus Cristi since it was discovered by the dates on which this Catholic holiday was celebrated, due to this invasion the aborigines set fire to houses and then fled , since they did not like the mistreatment of the expeditionaries.


Estos rumores de las grandes riquezas del territorio y su belleza fueron la causa por la que dos capitanes de la corona llegaron al territorio a eso de 1558, Fernando Loyola y Diego de Carvajal que después de enfrentarse y tener una fuerte disputa abandonaron el territorio.La nueva población de San Carlos de Priego was founded on the 14th of August 1786 by Francisco Lorenzo de Rivera.
The growth and prosperity of the colony lasted until the twentieth century when San Carlos ceased to become the obligatory passage of the Magdalena River to Medellin but also retained its agricultural vocation inherited by the Indians, the development of livestock and the nascent tourism were established as a new livelihood, until the time of displacement.
San Carlos es reconocido como la capital hidroeléctrica de Colombia gracias a la gran riqueza de sus aguas que generan el 29% de la energía nacional y por su biodiversidad en el 2015 se declara como área protegida el Corredor de las Camelias con una área de 12.718.26 hectáreas pertenecientes a los municipios de Guatapé, San Rafael , Granada y finalmente San Carlos que aporta el 57.30% del total del área protegida, por ser corredores biodiversos en la jurisdicción de Cornare, lo importante de esta área protegida es que es el corredor natural del cougar; in addition to one of the birds in danger of extinction, such as the cacique candela, the river otter; the meliponas bee, una especie que no tiene aguijón, no pica y que puede ser tenida en las fincas de los campesinos, donde las pueden trabajar y extraer su miel, que tiene propiedades medicinales, de ahí la importancia de que las familias campesinas asentadas en esta zona reciban un precio justo por sus cultivos para que ellos sea cuidadores de esta riqueza que estamos orgullosos de tener.